3VFF

BlaC E166A CDC-OMe Acyl-Intermediate Complex

Summary for 3VFF

• Entry DOI: 10.2210/pdb3vff/pdb
• Related: 3VFH 4EBI 4EBL 4EBM 4EBN 4EBO 4EBP
• Descriptor: Beta-lactamase, (2R)-2-[(1S)-1-(benzoylamino)-1-methoxy-2-oxoethyl]-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, PHOSPHATE ION, ... (4 entities in total)
• Functional Keywords: beta-lactamase, serine hydrolase, serine esterase, acyl-intermediate, hydrolase-hydrolase inhibitor complex, structural genomics, tb structural genomics consortium, tbsgc, hydrolase/hydrolase inhibitor
• Biological source: Mycobacterium tuberculosis
• Cellular location: Cell membrane; Lipid-anchor (Potential): P0C5C1
• Total number of polymer chains: 4
• Total formula weight: 123634.71

Authors

Mire, J.A.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2012-01-09, release date: 2012-09-19, Last modification date: 2023-09-13)

• Primary citation: Xie, H.,Mire, J.A.,Kong, Y.,Chang, M.,Sacchettini, J.C.,Cirillo, J.D.,Rao, J.; BlaC-Specific Fluorogenic Probes for Rapid Tuberculosis Detection; To be Published,

Experimental method

X-RAY DIFFRACTION (2.777 Å)