3VDQ

Crystal structure of alcaligenes faecalis D-3-hydroxybutyrate dehydrogenase in complex with NAD(+) and acetate

Replaces:  2ZEA

Summary for 3VDQ

• Entry DOI: 10.2210/pdb3vdq/pdb
• Related: 2YZ7 3VDR
• Descriptor: D-3-hydroxybutyrate dehydrogenase, ACETATE ION, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: nad dependent enzyme, hydroxybutyrate dehydrogenase, ketone bodies, oxidoreductase
• Biological source: Alcaligenes faecalis
• Total number of polymer chains: 4
• Total formula weight: 111587.62

Authors

Hoque, M.M.,Shimizu, S.,Hossain, M.T.,Yamamoto, T.,Suzuki, K.,Takenaka, A. (deposition date: 2012-01-06, release date: 2012-02-29, Last modification date: 2023-11-08)

• Primary citation: Hoque, M.M.,Shimizu, S.,Hossain, M.T.,Yamamoto, T.,Imamura, S.,Suzuki, K.,Tsunoda, M.,Amano, H.,Sekiguchi, T.,Takenaka, A.; The structures of Alcaligenes faecalis D-3-hydroxybutyrate dehydrogenase before and after NAD+ and acetate binding suggest a dynamical reaction mechanism as a member of the SDR family.; Acta Crystallogr.,Sect.D, 64:496-505, 2008; PubMed: 18453685; DOI: 10.1107/S0907444908004009

Experimental method

X-RAY DIFFRACTION (2.2 Å)