3VAW

Crystal structure of a smt fusion peptidyl-prolyl cis-trans isomerase with surface mutation v3i from burkholderia pseudomallei complexed with fk506

3VAW の概要

• エントリーDOI: 10.2210/pdb3vaw/pdb
• 関連するPDBエントリー: 2keo 2ko7 2l2s 3uf8 3uqa 3uqb 4DZ2 4DZ3 4FN2 4G50 4GGQ 4GIV
• 分子名称: Ubiquitin-like protein SMT3,Peptidyl-prolyl cis-trans isomerase, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN (3 entities in total)
• 機能のキーワード: ssgcid, isomerase, structural genomics, seattle structural genomics center for infectious disease, protein binding, protein binding-inhibitor complex, protein binding/inhibitor
• 由来する生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23819.88

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2011-12-29, 公開日: 2012-01-18, 最終更新日: 2023-09-13)

• 主引用文献: Begley, D.W.,Fox, D.,Jenner, D.,Juli, C.,Pierce, P.G.,Abendroth, J.,Muruthi, M.,Safford, K.,Anderson, V.,Atkins, K.,Barnes, S.R.,Moen, S.O.,Raymond, A.C.,Stacy, R.,Myler, P.J.,Staker, B.L.,Harmer, N.J.,Norville, I.H.,Holzgrabe, U.,Sarkar-Tyson, M.,Edwards, T.E.,Lorimer, D.D.; A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins.; Antimicrob.Agents Chemother., 58:1458-1467, 2014; PubMed: 24366729; DOI: 10.1128/AAC.01875-13

実験手法

X-RAY DIFFRACTION (1.55 Å)