3VAJ
Structure of U2AF65 variant with BrU5C6 DNA
Summary for 3VAJ
Entry DOI | 10.2210/pdb3vaj/pdb |
Related | 2G4B 2HZC 3VAF 3VAG 3VAH 3VAI 3VAK 3VAL 3VAM 3VAN 3VAO |
Descriptor | Splicing factor U2AF 65 kDa subunit, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*CP*U)-3'), 1,4-DIETHYLENE DIOXIDE, ... (7 entities in total) |
Functional Keywords | rna splicing factor, rna recognition motif, rna binding protein, rna binding protein-dna complex, rna binding protein/dna |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P26368 |
Total number of polymer chains | 4 |
Total formula weight | 44342.90 |
Authors | Jenkins, J.L.,Kielkopf, C.L. (deposition date: 2011-12-29, release date: 2013-02-13, Last modification date: 2024-02-28) |
Primary citation | Jenkins, J.L.,Agrawal, A.A.,Gupta, A.,Green, M.R.,Kielkopf, C.L. U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41:3859-3873, 2013 Cited by PubMed: 23376934DOI: 10.1093/nar/gkt046 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report