3V35

Aldose reductase complexed with a nitro compound

Summary for 3V35

• Entry DOI: 10.2210/pdb3v35/pdb
• Related: 3V36
• Descriptor: Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-[(5-nitro-1,3-thiazol-2-yl)carbamoyl]phenyl acetate, ... (5 entities in total)
• Functional Keywords: aldose reductase, oxidoreductase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P15121
• Total number of polymer chains: 1
• Total formula weight: 40801.54

Authors

Zheng, X.,Zhang, L.,Chen, Y.,Luo, H.,Hu, X. (deposition date: 2011-12-13, release date: 2012-08-29, Last modification date: 2023-11-08)

• Primary citation: Zheng, X.,Zhang, L.,Chen, W.,Chen, Y.,Xie, W.,Hu, X.; Partial inhibition of aldose reductase by nitazoxanide and its molecular basis.; Chemmedchem, 7:1921-1923, 2012; PubMed: 22890894; DOI: 10.1002/cmdc.201200333

Experimental method

X-RAY DIFFRACTION (1.9 Å)