3V16

An intramolecular pi-cation latch in phosphatidylinositol-specific phospholipase C from S.aureus controls substrate access to the active site

3V16 の概要

• エントリーDOI: 10.2210/pdb3v16/pdb
• 分子名称: 1-phosphatidylinositol phosphodiesterase, 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: pi-cation, tim barrel, phospholipase, lyase
• 由来する生物種: Staphylococcus aureus subsp. aureus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34499.77

構造登録者

Goldstein, R.I.,Cheng, J.,Stec, B.,Roberts, M.F. (登録日: 2011-12-09, 公開日: 2012-04-04, 最終更新日: 2023-09-13)

• 主引用文献: Goldstein, R.,Cheng, J.,Stec, B.,Roberts, M.F.; Structure of the S. aureus PI-Specific Phospholipase C Reveals Modulation of Active Site Access by a Titratable PI-Cation Latched Loop; Biochemistry, 51:2579-2587, 2012; PubMed: 22390775; DOI: 10.1021/bi300057q

実験手法

X-RAY DIFFRACTION (2.05 Å)