3V0S

Crystal Structure of Perakine Reductase, Founder Member of a Novel AKR Subfamily with Unique Conformational Changes during NADPH Binding

3V0S の概要

• エントリーDOI: 10.2210/pdb3v0s/pdb
• 関連するPDBエントリー: 3V0T 3V0U
• 分子名称: Perakine reductase, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE (3 entities in total)
• 機能のキーワード: perakine reductase, akr superfamily, oxidoreductase
• 由来する生物種: Rauvolfia serpentina (devilpepper)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37980.25

構造登録者

Sun, L.,Chen, Y.,Rajendran, C.,Panjikar, S.,Mueller, U.,Wang, M.,Rosenthal, C.,Mindnich, R.,Penning, T.M.,Stoeckigt, J. (登録日: 2011-12-08, 公開日: 2012-02-22, 最終更新日: 2023-11-08)

• 主引用文献: Sun, L.,Chen, Y.,Rajendran, C.,Mueller, U.,Panjikar, S.,Wang, M.,Mindnich, R.,Rosenthal, C.,Penning, T.M.,Stockigt, J.; Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding.; J.Biol.Chem., 287:11213-11221, 2012; PubMed: 22334702; DOI: 10.1074/jbc.M111.335521

実験手法

X-RAY DIFFRACTION (1.773 Å)