3V0R

Crystal structure of Alternaria alternata allergen Alt a 1

3V0R の概要

• エントリーDOI: 10.2210/pdb3v0r/pdb
• 分子名称: Major allergen Alt a 1, SULFATE ION, UNKNOWN ATOM OR ION, ... (6 entities in total)
• 機能のキーワード: beta-barrel, cell wall, unknown function
• 由来する生物種: Alternaria alternata (Alternaria rot fungus)
• 細胞内の位置: Secreted: P79085
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15572.04

構造登録者

Chruszcz, M.,Solberg, R.,Osinski, T.,Chapman, M.D.,Minor, W. (登録日: 2011-12-08, 公開日: 2012-06-13, 最終更新日: 2024-10-30)

主引用文献

Chruszcz, M.,Chapman, M.D.,Osinski, T.,Solberg, R.,Demas, M.,Porebski, P.J.,Majorek, K.A.,Pomes, A.,Minor, W.
Alternaria alternata allergen Alt a 1: a unique beta-barrel protein dimer found exclusively in fungi.
J.Allergy Clin.Immunol., 130:241-7.e9, 2012

PubMed Abstract: Alternaria species is one of the most common molds associated with allergic diseases, and 80% of Alternaria species-sensitive patients produce IgE antibodies to a major protein allergen, Alt a 1. The structure and function of Alt a 1 is unknown.

PubMed: 22664167
DOI: 10.1016/j.jaci.2012.03.047

実験手法

X-RAY DIFFRACTION (1.9 Å)