3V06

Crystal structure of S-6'-Me-3'-fluoro hexitol nucleic acid

Summary for 3V06

• Entry DOI: 10.2210/pdb3v06/pdb
• Related: 3V07
• Descriptor: DNA (5'-D(*GP*CP*GP*TP*AP*(F5H)P*AP*CP*GP*C)-3'), STRONTIUM ION (3 entities in total)
• Functional Keywords: a-form dna, 3'-fluoro hexitol nucleic acid, fhna, s-6'-me-fhna, antisense oligonucleotides, dna
• Total number of polymer chains: 2
• Total formula weight: 6269.72

Authors

Pallan, P.S.,Egli, M. (deposition date: 2011-12-07, release date: 2012-02-08, Last modification date: 2023-09-13)

• Primary citation: Pallan, P.S.,Yu, J.,Allerson, C.R.,Swayze, E.E.,Seth, P.,Egli, M.; Insights from crystal structures into the opposite effects on RNA affinity caused by the s- and R-6'-methyl backbone modifications of 3'-fluoro hexitol nucleic Acid.; Biochemistry, 51:7-9, 2012; PubMed: 22229409; DOI: 10.1021/bi201810r

Experimental method

X-RAY DIFFRACTION (1.53 Å)