3UYO
Crystal structure of monobody SH13/ABL1 SH2 domain complex
Summary for 3UYO
Entry DOI | 10.2210/pdb3uyo/pdb |
Related | 3K2M 3NCS |
Descriptor | Tyrosine-protein kinase ABL1, Monobody SH13, SULFATE ION, ... (4 entities in total) |
Functional Keywords | engineered binding protein, antibody mimic, protein-protein complex, sh2 domain, atp-binding, phosphoprotein, tyrosine-protein kinase, signaling protein-protein binding complex, signaling protein/protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor: P00519 |
Total number of polymer chains | 2 |
Total formula weight | 23872.24 |
Authors | Wojcik, J.B.,Koide, A.,Koide, S. (deposition date: 2011-12-06, release date: 2011-12-28, Last modification date: 2023-09-13) |
Primary citation | Koide, A.,Wojcik, J.,Gilbreth, R.N.,Hoey, R.J.,Koide, S. Teaching an old scaffold new tricks: monobodies constructed using alternative surfaces of the FN3 scaffold. J.Mol.Biol., 415:393-405, 2012 Cited by PubMed: 22198408DOI: 10.1016/j.jmb.2011.12.019 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.83 Å) |
Structure validation
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