3UYI
Crystal Structure of Perakine Reductase, Founder Member of a Novel AKR Subfamily with Unique Conformational Changes during NADPH Binding
Summary for 3UYI
| Entry DOI | 10.2210/pdb3uyi/pdb |
| Descriptor | Perakine reductase (2 entities in total) |
| Functional Keywords | akr superfamily, 8/6 barrel, perakine reductase, nadph, oxidoreductase |
| Biological source | Rauvolfia serpentina (devilpepper) |
| Total number of polymer chains | 1 |
| Total formula weight | 37229.66 |
| Authors | Sun, L.,Chen, Y.,Rajendran, C.,Panjikar, S.,Mueller, U.,Wang, M.,Rosenthal, C.,Mindnich, R.,Penning, T.M.,Stoeckigt, J. (deposition date: 2011-12-06, release date: 2012-02-22, Last modification date: 2023-11-08) |
| Primary citation | Sun, L.,Chen, Y.,Rajendran, C.,Mueller, U.,Panjikar, S.,Wang, M.,Mindnich, R.,Rosenthal, C.,Penning, T.M.,Stockigt, J. Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding. J.Biol.Chem., 287:11213-11221, 2012 Cited by PubMed: 22334702DOI: 10.1074/jbc.M111.335521 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.313 Å) |
Structure validation
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