3UOU
Crystal structure of the Kunitz-type protease inhibitor ShPI-1 Lys13Leu mutant in complex with pancreatic elastase
Summary for 3UOU
Entry DOI | 10.2210/pdb3uou/pdb |
Descriptor | Chymotrypsin-like elastase family member 1, Kunitz-type proteinase inhibitor SHPI-1, SULFATE ION, ... (5 entities in total) |
Functional Keywords | protein-protein interaction, hydrolase (serine protease), kunitz-type inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Stichodactyla helianthus (Carribean sea anemone) More |
Cellular location | Secreted: P00772 P31713 |
Total number of polymer chains | 2 |
Total formula weight | 33451.15 |
Authors | Garcia-Fernandez, R.,Perbandt, M.,Rehders, D.,Gonzalez-Gonzalez, Y.,Chavez, M.A.,Betzel, C.,Redecke, L. (deposition date: 2011-11-17, release date: 2012-11-21, Last modification date: 2023-09-13) |
Primary citation | Garcia-Fernandez, R.,Perbandt, M.,Rehders, D.,Ziegelmuller, P.,Piganeau, N.,Hahn, U.,Betzel, C.,Chavez, M.A.,Redecke, L. Three-dimensional Structure of a Kunitz-type Inhibitor in Complex with an Elastase-like Enzyme. J.Biol.Chem., 290:14154-14165, 2015 Cited by PubMed: 25878249DOI: 10.1074/jbc.M115.647586 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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