3UOU

Crystal structure of the Kunitz-type protease inhibitor ShPI-1 Lys13Leu mutant in complex with pancreatic elastase

3UOU の概要

• エントリーDOI: 10.2210/pdb3uou/pdb
• 分子名称: Chymotrypsin-like elastase family member 1, Kunitz-type proteinase inhibitor SHPI-1, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: protein-protein interaction, hydrolase (serine protease), kunitz-type inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Stichodactyla helianthus (Carribean sea anemone); 詳細
• 細胞内の位置: Secreted: P00772 P31713
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 33451.15

構造登録者

Garcia-Fernandez, R.,Perbandt, M.,Rehders, D.,Gonzalez-Gonzalez, Y.,Chavez, M.A.,Betzel, C.,Redecke, L. (登録日: 2011-11-17, 公開日: 2012-11-21, 最終更新日: 2023-09-13)

• 主引用文献: Garcia-Fernandez, R.,Perbandt, M.,Rehders, D.,Ziegelmuller, P.,Piganeau, N.,Hahn, U.,Betzel, C.,Chavez, M.A.,Redecke, L.; Three-dimensional Structure of a Kunitz-type Inhibitor in Complex with an Elastase-like Enzyme.; J.Biol.Chem., 290:14154-14165, 2015; PubMed: 25878249; DOI: 10.1074/jbc.M115.647586

実験手法