3UM3

Crystal structure of the Brox Bro1 domain in complex with the C-terminal tail of CHMP4B

Summary for 3UM3

Entry DOI	10.2210/pdb3um3/pdb
Related	3R9M 3ULY 3UM0 3UM1 3UM2
Descriptor	BRO1 domain-containing protein BROX, Charged multivesicular body protein 4b (2 entities in total)
Functional Keywords	alpha-helix of c-terminal tail of chmp4b, escrt-iii, chmps, membrane protein-transport protein complex, brox, membrane protein/transport protein
Biological source	Homo sapiens (human) More
Cellular location	Membrane; Lipid-anchor (Potential): Q5VW32 Cytoplasm, cytosol: Q9H444
Total number of polymer chains	2
Total formula weight	58221.65
Authors	Jiang, J.S.,Mu, R.L.,Xiao, T. (deposition date: 2011-11-12, release date: 2012-04-18, Last modification date: 2023-09-13)
Primary citation	Mu, R.,Dussupt, V.,Jiang, J.,Sette, P.,Rudd, V.,Chuenchor, W.,Bello, N.F.,Bouamr, F.,Xiao, T.S. Two Distinct Binding Modes Define the Interaction of Brox with the C-Terminal Tails of CHMP5 and CHMP4B. Structure, 20:887-898, 2012 Cited by PubMed: 22484091 DOI: 10.1016/j.str.2012.03.001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.8 Å)

Structure validation