3UIB

Map kinase LMAMPK10 from leishmania major in complex with SB203580

Summary for 3UIB

• Entry DOI: 10.2210/pdb3uib/pdb
• Related: 3PG1
• Descriptor: mitogen-activated protein kinase, 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE (3 entities in total)
• Functional Keywords: eukariotic protein kinase fold, transferase
• Biological source: Leishmania major
• Total number of polymer chains: 1
• Total formula weight: 41836.81

Authors

Horjales, S.,Schmidt-Arras, D.,Leclercq, O.,Spath, G.,Buschiazzo, A. (deposition date: 2011-11-04, release date: 2012-09-19, Last modification date: 2024-02-28)

• Primary citation: Horjales, S.,Schmidt-Arras, D.,Limardo, R.R.,Leclercq, O.,Obal, G.,Prina, E.,Turjanski, A.G.,Spath, G.F.,Buschiazzo, A.; The Crystal Structure of the MAP Kinase LmaMPK10 from Leishmania Major Reveals Parasite-Specific Features and Regulatory Mechanisms.; Structure, 20:1649-1660, 2012; PubMed: 22884419; DOI: 10.1016/j.str.2012.07.005

Experimental method

X-RAY DIFFRACTION (2.65 Å)