3UEM

Crystal structure of human PDI bb'a' domains

Summary for 3UEM

Entry DOI	10.2210/pdb3uem/pdb
Descriptor	Protein disulfide-isomerase, (4S,5S)-1,2-DITHIANE-4,5-DIOL (3 entities in total)
Functional Keywords	protein disulfide isomerase, thioredoxin-like domain, chaperone
Biological source	Homo sapiens (human)
Cellular location	Endoplasmic reticulum lumen: P07237
Total number of polymer chains	1
Total formula weight	40900.02
Authors	Yu, J.,Wang, C.,Huo, L.,Feng, W.,Wang, C.-C. (deposition date: 2011-10-30, release date: 2011-11-23, Last modification date: 2024-03-20)
Primary citation	Wang, C.,Yu, J.,Huo, L.,Wang, L.,Feng, W.,Wang, C.-C. Human protein-disulfide isomerase is a redox-regulated chaperone activated by oxidation of domain a' J.Biol.Chem., 287:1139-1149, 2012 Cited by PubMed: 22090031 DOI: 10.1074/jbc.M111.303149 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.29 Å)

Structure validation