3UDW
Crystal structure of the immunoreceptor TIGIT in complex with Poliovirus receptor (PVR/CD155/necl-5) D1 domain
Summary for 3UDW
Entry DOI | 10.2210/pdb3udw/pdb |
Descriptor | T cell immunoreceptor with Ig and ITIM domains, Poliovirus receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | pvr tigit igsf signal transduction immunology, igsf, cell surface receptor signalling, glycosylation, membrane protein, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 51017.23 |
Authors | Rouge, L.,Stengel, K.F.,Yin, J.P.,Bazan, F.J.,Wiesmann, C. (deposition date: 2011-10-28, release date: 2012-03-14, Last modification date: 2020-07-29) |
Primary citation | Stengel, K.F.,Harden-Bowles, K.,Yu, X.,Rouge, L.,Yin, J.,Comps-Agrar, L.,Wiesmann, C.,Bazan, J.F.,Eaton, D.L.,Grogan, J.L. Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering. Proc.Natl.Acad.Sci.USA, 109:5399-5404, 2012 Cited by PubMed: 22421438DOI: 10.1073/pnas.1120606109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.903 Å) |
Structure validation
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