3UDW

Crystal structure of the immunoreceptor TIGIT in complex with Poliovirus receptor (PVR/CD155/necl-5) D1 domain

3UDW の概要

• エントリーDOI: 10.2210/pdb3udw/pdb
• 分子名称: T cell immunoreceptor with Ig and ITIM domains, Poliovirus receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: pvr tigit igsf signal transduction immunology, igsf, cell surface receptor signalling, glycosylation, membrane protein, signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 51017.23

構造登録者

Rouge, L.,Stengel, K.F.,Yin, J.P.,Bazan, F.J.,Wiesmann, C. (登録日: 2011-10-28, 公開日: 2012-03-14, 最終更新日: 2020-07-29)

• 主引用文献: Stengel, K.F.,Harden-Bowles, K.,Yu, X.,Rouge, L.,Yin, J.,Comps-Agrar, L.,Wiesmann, C.,Bazan, J.F.,Eaton, D.L.,Grogan, J.L.; Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering.; Proc.Natl.Acad.Sci.USA, 109:5399-5404, 2012; PubMed: 22421438; DOI: 10.1073/pnas.1120606109

実験手法

X-RAY DIFFRACTION (2.903 Å)