3UD8

Crystal Structure Analysis of FGF1-Disaccharide(NI22) complex

Summary for 3UD8

Entry DOI	10.2210/pdb3ud8/pdb
Related	3UD7 3UD9 3UDA
Descriptor	Heparin-binding growth factor 1, 2-deoxy-3-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, PHOSPHATE ION, ... (4 entities in total)
Functional Keywords	heparin/heparan sulfate binding, hormone
Biological source	Homo sapiens (human)
Total number of polymer chains	3
Total formula weight	48766.64
Authors	Hung, S.-C.,Shi, Z. (deposition date: 2011-10-27, release date: 2012-11-28, Last modification date: 2023-11-01)
Primary citation	Hu, Y.-P.,Zhong, Y.-Q.,Chen, Z.-G.,Chen, C.-Y.,Shi, Z.,Zulueta, M.M.L.,Ku, C.-C.,Lee, P.-Y.,Wang, C.-C.,Hung, S.-C. Divergent synthesis of 48 heparan sulfate-based disaccharides and probing the specific sugar-fibroblast growth factor-1 interaction J.Am.Chem.Soc., 134:20722-20727, 2012 Cited by PubMed: 23240683 DOI: 10.1021/ja3090065 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.37 Å)

Structure validation