3U7H
Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTTp)
Summary for 3U7H
Entry DOI | 10.2210/pdb3u7h/pdb |
Related | 1YJ5 3U7E 3U7f 3u7g |
Descriptor | Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ... (6 entities in total) |
Functional Keywords | protein-dna complex, had family, pnkp, dna repair, phosphatase, hydrolase, transferase-dna complex, transferase/dna |
Biological source | Mus musculus (mouse) More |
Cellular location | Nucleus : Q9JLV6 |
Total number of polymer chains | 2 |
Total formula weight | 44404.43 |
Authors | Coquelle, N.,Havali, Z.,Bernstein, N.,Green, R.,Glover, J.N.M. (deposition date: 2011-10-13, release date: 2011-12-14, Last modification date: 2017-11-08) |
Primary citation | Coquelle, N.,Havali-Shahriari, Z.,Bernstein, N.,Green, R.,Glover, J.N. Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates. Proc.Natl.Acad.Sci.USA, 108:21022-21027, 2011 Cited by PubMed: 22171004DOI: 10.1073/pnas.1112036108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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