Crystal structure of the DB1883-D(CGCGAATTCGCG)2 complex at 1.24 A resolution

Summary for 3U0U

Related3U05 3U08
Descriptor5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', 2-(4'-carbamimidoylbiphenyl-4-yl)-1H-indole-6-carboximidamide, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsdouble helix, minor groove, dna minor groove binder, db1883, mg2+, dna
Total number of polymer chains2
Total molecular weight7753.12
Wei, D.G.,Neidle, S. (deposition date: 2011-09-29, release date: 2012-09-12, Last modification date: 2014-01-08)
Primary citation
Wei, D.,Wilson, W.D.,Neidle, S.
Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster.
J.Am.Chem.Soc., 135:1369-1377, 2013
PubMed: 23276263 (PDB entries with the same primary citation)
DOI: 10.1021/ja308952y
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRSRZ outliers0.24140MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution