3TZF
Crystal Structure of the Yersinia pestis Dihydropteroate Synthase with Sulfonamide Drug Complex.
Summary for 3TZF
Entry DOI | 10.2210/pdb3tzf/pdb |
Related | 3TYU 3TYZ 3TZN |
Descriptor | 7,8-dihydropteroate synthase, 6-HYDROXYMETHYLPTERIN-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | dihydropteroate synthase, sulfonamide complex, tim barrel, transferase-inhibitor-antibiotic complex, transferase-antibiotic-inhibitor complex, transferase/antibiotic/inhibitor |
Biological source | Yersinia pestis |
Total number of polymer chains | 2 |
Total formula weight | 61643.59 |
Authors | |
Primary citation | Yun, M.K.,Wu, Y.,Li, Z.,Zhao, Y.,Waddell, M.B.,Ferreira, A.M.,Lee, R.E.,Bashford, D.,White, S.W. Catalysis and sulfa drug resistance in dihydropteroate synthase. Science, 335:1110-1114, 2012 Cited by PubMed: 22383850DOI: 10.1126/science.1214641 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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