3TZ6

Crystal structure of Aspartate semialdehyde dehydrogenase Complexed With inhibitor SMCS (CYS) And Phosphate From Mycobacterium tuberculosis H37Rv

Summary for 3TZ6

• Entry DOI: 10.2210/pdb3tz6/pdb
• Related: 3LLG
• Descriptor: Aspartate-semialdehyde dehydrogenase, CYSTEINE, GLYCEROL, ... (5 entities in total)
• Functional Keywords: asadh, asd, asa, dehydrogenase, amino-acid biosynthesis, diaminopimelate biosynthesis, lysine biosynthesis, smcs, oxidoreductase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 1
• Total formula weight: 37107.67

Authors

Vyas, R.,Tewari, R.,Weiss, M.S.,Karthikeyan, S. (deposition date: 2011-09-27, release date: 2012-05-30, Last modification date: 2023-11-01)

• Primary citation: Vyas, R.,Tewari, R.,Weiss, M.S.,Karthikeyan, S.; Structures of ternary complexes of aspartate-semialdehyde dehydrogenase (Rv3708c) from Mycobacterium tuberculosis H37Rv; Acta Crystallogr.,Sect.D, 68:671-679, 2012; PubMed: 22683789; DOI: 10.1107/S0907444912007330

Experimental method

X-RAY DIFFRACTION (1.95 Å)