3TVB

A Highly Symmetric DNA G-4 Quadruplex/drug Complex

Summary for 3TVB

• Entry DOI: 10.2210/pdb3tvb/pdb
• Descriptor: DNA (5'-D(*GP*GP*GP*G)-3'), DAUNOMYCIN, SODIUM ION, ... (5 entities in total)
• Functional Keywords: g-4 quadruplex, daunomycin, dna-drug complex, dna-antibiotic complex, dna/antibiotic
• Total number of polymer chains: 2
• Total formula weight: 4886.34

Authors

Clark, G.R.,Pytel, P.D.,Squire, C.J. (deposition date: 2011-09-19, release date: 2012-03-14, Last modification date: 2024-02-28)

• Primary citation: Clark, G.R.,Pytel, P.D.,Squire, C.J.; The high-resolution crystal structure of a parallel intermolecular DNA G-4 quadruplex/drug complex employing syn glycosyl linkages.; Nucleic Acids Res., 40:5731-5738, 2012; PubMed: 22373921; DOI: 10.1093/nar/gks193

Experimental method

X-RAY DIFFRACTION (1.08 Å)