3TUP

Crystal structure of human mitochondrial PheRS complexed with tRNAPhe in the active open state

Summary for 3TUP

• Entry DOI: 10.2210/pdb3tup/pdb
• Related: 1PYS 3CMQ
• Descriptor: Phenylalanyl-tRNA synthetase, mitochondrial, Thermus thermophilus tRNAPhe (2 entities in total)
• Functional Keywords: class ii aars, rrm fold, aminoacylation, mitochondria, ligase-rna complex, ligase/rna
• Biological source: Homo sapiens (human); More
• Cellular location: Mitochondrion matrix (Potential): O95363
• Total number of polymer chains: 2
• Total formula weight: 72992.57

Authors

Safro, M.,Klipcan, L.,Moor, N.,Finarov, I.,Kessler, N.,Sukhanova, M. (deposition date: 2011-09-17, release date: 2011-11-23, Last modification date: 2024-02-28)

• Primary citation: Klipcan, L.,Moor, N.,Finarov, I.,Kessler, N.,Sukhanova, M.,Safro, M.G.; Crystal Structure of Human Mitochondrial PheRS Complexed with tRNA(Phe) in the Active "Open" State.; J.Mol.Biol., 415:527-537, 2012; PubMed: 22137894; DOI: 10.1016/j.jmb.2011.11.029

Experimental method

X-RAY DIFFRACTION (3.05 Å)