3TT9

Crystal structure of the stable degradation fragment of human plakophilin 2 isoform a (PKP2a) C752R variant

Summary for 3TT9

Entry DOI	10.2210/pdb3tt9/pdb
Descriptor	Plakophilin-2, GLYCEROL (3 entities in total)
Functional Keywords	cell adhesion
Biological source	Homo sapiens (human)
Cellular location	Nucleus: Q99959
Total number of polymer chains	1
Total formula weight	26398.24
Authors	Schuetz, A.,Roske, Y.,Gerull, B.,Heinemann, U. (deposition date: 2011-09-14, release date: 2012-08-01, Last modification date: 2024-03-13)
Primary citation	Kirchner, F.,Schuetz, A.,Boldt, L.H.,Martens, K.,Dittmar, G.,Haverkamp, W.,Thierfelder, L.,Heinemann, U.,Gerull, B. Molecular insights into arrhythmogenic right ventricular cardiomyopathy caused by plakophilin-2 missense mutations. Circ Cardiovasc Genet, 5:400-411, 2012 Cited by PubMed: 22781308 DOI: 10.1161/CIRCGENETICS.111.961854 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation