3TOJ

Structure of the SPRY domain of human Ash2L

Summary for 3TOJ

DescriptorSet1/Ash2 histone methyltransferase complex subunit ASH2 (2 entities in total)
Functional Keywordshistone methyltransferase, transcription, spry domain, protein binding, histone methylation, rbbp5, dpy-30, nuclear
Biological sourceHomo sapiens (human)
Cellular locationNucleus  Q9UBL3
Total number of polymer chains2
Total molecular weight47870.11
Authors
Chen, Y.,Cao, F.,Wan, B.,Dou, Y.,Lei, M. (deposition date: 2011-09-05, release date: 2012-01-25, Last modification date: 2017-08-23)
Primary citation
Chen, Y.,Cao, F.,Wan, B.,Dou, Y.,Lei, M.
Structure of the SPRY domain of human Ash2L and its interactions with RbBP5 and DPY30.
Cell Res., 22:598-602, 2012
PubMed: 22231628 (PDB entries with the same primary citation)
DOI: 10.1038/cr.2012.9
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.07 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.20030.8%0.3%1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution