3TNE

The crystal structure of protease Sapp1p from Candida parapsilosis in complex with the HIV protease inhibitor ritonavir

Summary for 3TNE

Entry DOI	10.2210/pdb3tne/pdb
Related	3FV3
Related PRD ID	PRD_001001
Descriptor	Secreted aspartic protease, RITONAVIR (3 entities in total)
Functional Keywords	aspartic acid endopeptidases, catalytic domain, ritonavir, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Candida parapsilosis (Yeast)
Total number of polymer chains	2
Total formula weight	73172.21
Authors	Dostal, J.,Brynda, J.,Hruskova-Heidingsfeldova, O.,Pachl, P.,Pichova, I.,Rezacova, P. (deposition date: 2011-09-01, release date: 2012-03-07, Last modification date: 2012-12-12)
Primary citation	Dostal, J.,Brynda, J.,Hruskova-Heidingsfeldova, O.,Pachl, P.,Pichova, I.,Rezacova, P. The crystal structure of protease Sapp1p from Candida parapsilosis in complex with the HIV protease inhibitor ritonavir. J Enzyme Inhib Med Chem, 27:160-165, 2012 Cited by PubMed: 22146051 DOI: 10.3109/14756366.2011.627508 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation