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3TKZ

Structure of the SHP-2 N-SH2 domain in a 1:2 complex with RVIpYFVPLNR peptide

Summary for 3TKZ
Entry DOI10.2210/pdb3tkz/pdb
Related3TL0
DescriptorTyrosine-protein phosphatase non-receptor type 11, PROTEIN (RVIpYFVPLNR peptide) (3 entities in total)
Functional Keywordssh2 domain, protein protein interactions, ptr residues, hydrolase-peptide complex, hydrolase/peptide
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm: Q06124
Total number of polymer chains3
Total formula weight15005.79
Authors
Zhang, Y.,Zhang, J.,Yuan, C.,Hard, R.L.,Park, I.H.,Li, C.,Bell, C.E.,Pei, D. (deposition date: 2011-08-29, release date: 2011-10-26, Last modification date: 2023-12-06)
Primary citationZhang, Y.,Zhang, J.,Yuan, C.,Hard, R.L.,Park, I.H.,Li, C.,Bell, C.,Pei, D.
Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain.
Biochemistry, 50:7637-7646, 2011
Cited by
PubMed: 21800896
DOI: 10.1021/bi200439v
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

217705

건을2024-03-27부터공개중

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