3TKZ
Structure of the SHP-2 N-SH2 domain in a 1:2 complex with RVIpYFVPLNR peptide
Summary for 3TKZ
Entry DOI | 10.2210/pdb3tkz/pdb |
Related | 3TL0 |
Descriptor | Tyrosine-protein phosphatase non-receptor type 11, PROTEIN (RVIpYFVPLNR peptide) (3 entities in total) |
Functional Keywords | sh2 domain, protein protein interactions, ptr residues, hydrolase-peptide complex, hydrolase/peptide |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm: Q06124 |
Total number of polymer chains | 3 |
Total formula weight | 15005.79 |
Authors | Zhang, Y.,Zhang, J.,Yuan, C.,Hard, R.L.,Park, I.H.,Li, C.,Bell, C.E.,Pei, D. (deposition date: 2011-08-29, release date: 2011-10-26, Last modification date: 2023-12-06) |
Primary citation | Zhang, Y.,Zhang, J.,Yuan, C.,Hard, R.L.,Park, I.H.,Li, C.,Bell, C.,Pei, D. Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain. Biochemistry, 50:7637-7646, 2011 Cited by PubMed: 21800896DOI: 10.1021/bi200439v PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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