3TH5
Crystal structure of wild-type RAC1
Summary for 3TH5
Entry DOI | 10.2210/pdb3th5/pdb |
Related | 3SBD 3SBE 4GZL 4GZM |
Descriptor | Ras-related C3 botulinum toxin substrate 1, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | rossmann fold, gtpase, gtp binding, protein binding, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Lipid-anchor; Cytoplasmic side (By similarity): P63000 |
Total number of polymer chains | 2 |
Total formula weight | 46561.08 |
Authors | Ha, B.H.,Boggon, T.J. (deposition date: 2011-08-18, release date: 2012-07-18, Last modification date: 2023-09-13) |
Primary citation | Krauthammer, M.,Kong, Y.,Ha, B.H.,Evans, P.,Bacchiocchi, A.,McCusker, J.P.,Cheng, E.,Davis, M.J.,Goh, G.,Choi, M.,Ariyan, S.,Narayan, D.,Dutton-Regester, K.,Capatana, A.,Holman, E.C.,Bosenberg, M.,Sznol, M.,Kluger, H.M.,Brash, D.E.,Stern, D.F.,Materin, M.A.,Lo, R.S.,Mane, S.,Ma, S.,Kidd, K.K.,Hayward, N.K.,Lifton, R.P.,Schlessinger, J.,Boggon, T.J.,Halaban, R. Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat.Genet., 44:1006-1014, 2012 Cited by PubMed: 22842228DOI: 10.1038/ng.2359 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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