3TEM
Quinone Oxidoreductase (NQ02) bound to the imidazoacridin-6-one 6a1
Summary for 3TEM
Entry DOI | 10.2210/pdb3tem/pdb |
Related | 3TE7 |
Descriptor | Ribosyldihydronicotinamide dehydrogenase [quinone], ZINC ION, FLAVIN-ADENINE DINUCLEOTIDE, ... (6 entities in total) |
Functional Keywords | oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P16083 |
Total number of polymer chains | 2 |
Total formula weight | 53786.11 |
Authors | Dunstan, M.S.,Leys, D. (deposition date: 2011-08-15, release date: 2011-09-21, Last modification date: 2024-02-28) |
Primary citation | Dunstan, M.S.,Barnes, J.,Humphries, M.,Whitehead, R.C.,Bryce, R.A.,Leys, D.,Stratford, I.J.,Nolan, K.A. Novel Inhibitors of NRH:Quinone Oxidoreductase 2 (NQO2): Crystal Structures, Biochemical Activity, and Intracellular Effects of Imidazoacridin-6-ones. J.Med.Chem., 54:6597-6611, 2011 Cited by PubMed: 21859103DOI: 10.1021/jm200416e PDB entries with the same primary citation |
Experimental method |
Structure validation
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