3TDL

Structure of human serum albumin in complex with DAUDA

Summary for 3TDL

DescriptorSerum albumin, MYRISTIC ACID, 11-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)undecanoic acid (3 entities in total)
Functional Keywordsprotein-drug complex, human serum albumin, myristate, dauda, fluorescent fatty acid analogue, protein binding, transport protein
Biological sourceHomo sapiens (human)
Cellular locationSecreted P02768
Total number of polymer chains1
Total molecular weight68353.89
Authors
Wang, Y.,Luo, Z.,Shi, X.,Wang, H.,Nie, L. (deposition date: 2011-08-11, release date: 2012-06-27)
Primary citation
Wang, Y.,Luo, Z.,Shi, X.,Wang, H.,Nie, L.,Huang, M.
A fluorescent fatty acid probe, DAUDA, selectively displaces two myristates bound in human serum albumin
Protein Sci., 20:2095-2101, 2011
PubMed: 21997768 (PDB entries with the same primary citation)
DOI: 10.1002/pro.749
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.314431.7%15.0%2.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution