3TCL

Crystal Structure of HIV-1 Neutralizing Antibody CH04

Summary for 3TCL

• Entry DOI: 10.2210/pdb3tcl/pdb
• Related: 3U2S 3U36 3U46 3U4B
• Descriptor: CH04 Heavy Chain Fab, CH04 Light Chain Fab, IMIDAZOLE, ... (4 entities in total)
• Functional Keywords: ig, immunoglobulin, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 98481.33

Authors

Louder, R.K.,McLellan, J.S.,Pancera, M.,Yang, Y.,Zhang, B.,Bonsignori, M.,Kwong, P.D. (deposition date: 2011-08-09, release date: 2011-11-30, Last modification date: 2023-09-13)

• Primary citation: McLellan, J.S.,Pancera, M.,Carrico, C.,Gorman, J.,Julien, J.P.,Khayat, R.,Louder, R.,Pejchal, R.,Sastry, M.,Dai, K.,O'Dell, S.,Patel, N.,Shahzad-Ul-Hussan, S.,Yang, Y.,Zhang, B.,Zhou, T.,Zhu, J.,Boyington, J.C.,Chuang, G.Y.,Diwanji, D.,Georgiev, I.,Do Kwon, Y.,Lee, D.,Louder, M.K.,Moquin, S.,Schmidt, S.D.,Yang, Z.Y.,Bonsignori, M.,Crump, J.A.,Kapiga, S.H.,Sam, N.E.,Haynes, B.F.,Burton, D.R.,Koff, W.C.,Walker, L.M.,Phogat, S.,Wyatt, R.,Orwenyo, J.,Wang, L.X.,Arthos, J.,Bewley, C.A.,Mascola, J.R.,Nabel, G.J.,Schief, W.R.,Ward, A.B.,Wilson, I.A.,Kwong, P.D.; Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9.; Nature, 480:336-343, 2011; PubMed: 22113616; DOI: 10.1038/nature10696

Experimental method

X-RAY DIFFRACTION (1.906 Å)