3T4P

Crystal structure of O-Acetyl Serine Sulfhydrylase from Leishmania donovani in complex with designed tetrapeptide

Summary for 3T4P

• Entry DOI: 10.2210/pdb3t4p/pdb
• Related: 3spx 3tbh
• Descriptor: O-acetyl serine sulfhydrylase, tetrapeptide DWSI, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
• Functional Keywords: cysteine synthase, the tryptophan synthase family (fold type ii), serine acetyl transferase, sulfhydrylase, sulfhydrylase-inhibitor complex, peptide-oass complex, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Leishmania donovani; More
• Total number of polymer chains: 2
• Total formula weight: 36568.37

Authors

Raj, I.,Gourinath, S. (deposition date: 2011-07-26, release date: 2012-08-01, Last modification date: 2023-12-06)

• Primary citation: Raj, I.,Kumar, S.,Gourinath, S.; The narrow active-site cleft of O-acetylserine sulfhydrylase from Leishmania donovani allows complex formation with serine acetyltransferases with a range of C-terminal sequences; Acta Crystallogr.,Sect.D, 68:909-919, 2012; PubMed: 22868756; DOI: 10.1107/S0907444912016459

Experimental method

X-RAY DIFFRACTION (1.77 Å)