3T4G
AIIGLMV segment from Alzheimer's Amyloid-Beta displayed on 54-membered macrocycle scaffold
Summary for 3T4G
| Entry DOI | 10.2210/pdb3t4g/pdb |
| Descriptor | Cyclic pseudo-peptide (ORN)AIIGLMV(ORN)KF(HAO)(4BF)K, (4S)-2-METHYL-2,4-PENTANEDIOL (2 entities in total) |
| Functional Keywords | amyloid-related, macrocycle, hao, unknown function |
| Total number of polymer chains | 2 |
| Total formula weight | 4212.94 |
| Authors | Zhao, M.,Liu, C.,Cheng, P.N.,Eisenberg, D.,Nowick, J.S. (deposition date: 2011-07-26, release date: 2012-10-31, Last modification date: 2023-11-15) |
| Primary citation | Cheng, P.N.,Liu, C.,Zhao, M.,Eisenberg, D.,Nowick, J.S. Amyloid beta-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity. Nat Chem, 4:927-933, 2012 Cited by PubMed: 23089868DOI: 10.1038/nchem.1433 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report
