3T4A
Structure of a truncated form of Staphylococcal Complement Inhibitor B bound to human C3c at 3.4 Angstrom resolution
3T4A の概要
エントリーDOI | 10.2210/pdb3t4a/pdb |
関連するPDBエントリー | 3T46 3T47 3T48 3T49 |
分子名称 | Complement C3 beta chain, Complement C3c alpha' chain fragment 1, Complement C3c alpha' chain fragment 2, ... (4 entities in total) |
機能のキーワード | age-related macular degeneration, cleavage on pair of basic residues, complement alternate pathway, complement pathway, disease mutation, disulfide bond, glycoprotein, hemolytic uremic syndrome, immunity, inflammatory response, innate immunity, phosphoprotein, secreted, thioester bond, immune system |
由来する生物種 | Staphylococcus aureus subsp. aureus 詳細 |
細胞内の位置 | Secreted: P01024 P01024 P01024 |
タンパク質・核酸の鎖数 | 8 |
化学式量合計 | 285532.87 |
構造登録者 | |
主引用文献 | Garcia, B.L.,Summers, B.J.,Lin, Z.,Ramyar, K.X.,Ricklin, D.,Kamath, D.V.,Fu, Z.Q.,Lambris, J.D.,Geisbrecht, B.V. Diversity in the C3b Convertase Contact Residues and Tertiary Structures of the Staphylococcal Complement Inhibitor (SCIN) Protein Family. J.Biol.Chem., 287:628-640, 2012 Cited by PubMed: 22086928DOI: 10.1074/jbc.M111.298984 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (3.4 Å) |
構造検証レポート
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