3T30

Human nucleoplasmin (Npm2): a histone chaperone in oocytes and early embryos

Summary for 3T30

DescriptorNucleoplasmin-2 (2 entities in total)
Functional Keywordsbeta-barrel jelly roll topology, histone chaperone, h2a-h2b dimer and h3-h4 tetramer, oocytes and early embryos, chaperone
Biological sourceHomo sapiens (human)
Cellular locationNucleus (By similarity) Q86SE8
Total number of polymer chains10
Total molecular weight123944.25
Authors
Platonova, O.,Head, J.F.,Akey, C.W. (deposition date: 2011-07-23, release date: 2011-09-21, Last modification date: 2011-11-30)
Primary citation
Platonova, O.,Akey, I.V.,Head, J.F.,Akey, C.W.
Crystal structure and function of human nucleoplasmin (npm2): a histone chaperone in oocytes and embryos.
Biochemistry, 50:8078-8089, 2011
PubMed: 21863821 (PDB entries with the same primary citation)
DOI: 10.1021/bi2006652
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.247160.1%7.1%11.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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More Biological unit images

Molmil generated image of 3t30
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Molmil generated image of 3t30
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (3t30.pdb1.gz [81.69 KB])
Coordinate files for Biological unit (3t30.pdb2.gz [81.8 KB])