3SVJ

Strep Peptide Deformylase with a time dependent thiazolidine amide

3SVJ の概要

• エントリーDOI: 10.2210/pdb3svj/pdb
• 関連するPDBエントリー: 3STR
• 分子名称: Peptide deformylase 3, SULFATE ION, (4R)-3-(4-[4-(2-chlorophenyl)piperazin-1-yl]-6-{[2-methyl-6-(methylcarbamoyl)phenyl]amino}-1,3,5-triazin-2-yl)-N-methyl-1,3-thiazolidine-4-carboxamide, ... (6 entities in total)
• 機能のキーワード: alpha-beta, peptide deformylase, metal binding protein, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Streptococcus pneumoniae
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23790.14

構造登録者

Campobasso, N.,Ward, P. (登録日: 2011-07-12, 公開日: 2011-07-27, 最終更新日: 2014-11-12)

• 主引用文献: Totoritis, R.,Duraiswami, C.,Taylor, A.N.,Kerrigan, J.J.,Campobasso, N.,Smith, K.J.,Ward, P.,King, B.W.,Murrayz-Thompson, M.,Jones, A.D.,Van Aller, G.S.,Aubart, K.M.,Zalacain, M.,Thrall, S.H.,Meek, T.D.,Schwartz, B.; Understanding the origins of time-dependent inhibition by polypeptide deformylase inhibitors.; Biochemistry, 50:6642-6654, 2011; PubMed: 21711014; DOI: 10.1021/bi200655g

実験手法

X-RAY DIFFRACTION (1.55 Å)