3STG

Crystal structure of A58P, DEL(N59), and loop 7 truncated mutant of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis

3STG の概要

• エントリーDOI: 10.2210/pdb3stg/pdb
• 関連するPDBエントリー: 3STC 3STE 3STF
• 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION (3 entities in total)
• 機能のキーワード: manno-octulosonate, synthase, lipopolysaccharide, kdop, kdo8 kdops, kdo8ps, tim barrel, biosynthesis, transferase, lyase, lipopolysaccharide biosynthesis
• 由来する生物種: Neisseria meningitidis
• 細胞内の位置: Cytoplasm (By similarity): Q9JZ55
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 118138.48

構造登録者

Allison, T.M.,Jameson, G.B.,Parker, E.J. (登録日: 2011-07-09, 公開日: 2011-11-23, 最終更新日: 2023-11-01)

• 主引用文献: Allison, T.M.,Hutton, R.D.,Jiao, W.,Gloyne, B.J.,Nimmo, E.B.,Jameson, G.B.,Parker, E.J.; An Extended (beta)7(alpha)7 Substrate-Binding Loop Is Essential for Efficient Catalysis by 3-Deoxy-D-manno-Octulosonate 8-Phosphate Synthase; Biochemistry, 50:9318-9327, 2011; PubMed: 21942786; DOI: 10.1021/bi201231e

実験手法

X-RAY DIFFRACTION (2.2 Å)