3SQP

Structure of human glutathione reductase complexed with pyocyanin, an agent with antimalarial activity

3SQP の概要

• エントリーDOI: 10.2210/pdb3sqp/pdb
• 分子名称: Glutathione reductase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION, ... (6 entities in total)
• 機能のキーワード: cellular reductants, glutathione reductase, plasmodium falciparum, pyocyanin, alternative initiation, flavoprotein, mitochondrion, oxidoreductase, phosphoprotein, redox-active center, transit peptide, oxidoreductase-antibiotic complex, oxidoreductase/antibiotic
• 由来する生物種: Homo sapiens
• 細胞内の位置: Isoform Mitochondrial: Mitochondrion. Isoform Cytoplasmic: Cytoplasm: P00390
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 105832.49

構造登録者

Fritz-Wolf, K.,Schirmer, R.H.,Koenig, I.,Goebel, U. (登録日: 2011-07-06, 公開日: 2011-09-14, 最終更新日: 2023-09-13)

• 主引用文献: Kasozi, D.M.,Gromer, S.,Adler, H.,Zocher, K.,Rahlfs, S.,Wittlin, S.,Fritz-Wolf, K.,Schirmer, R.H.,Becker, K.; The bacterial redox signaller pyocyanin as an antiplasmodial agent: comparisons with its thioanalog methylene blue.; Redox Rep., 16:154-165, 2011; PubMed: 21888766; DOI: 10.1179/174329211X13049558293678

実験手法

X-RAY DIFFRACTION (2.21 Å)