3SM9

Crystal Structure of Metabotropic glutamate receptor 3 precursor in presence of LY341495 antagonist

Summary for 3SM9

DescriptorMetabotropic glutamate receptor 3, SULFATE ION, 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine, ... (5 entities in total)
Functional Keywordsstructural genomics, structural genomics consortium, sgc, cell membrane, g-protein coupled receptor, glycoprotein, membrane, olfaction, phosphoprotein, receptor, sensory transduction, transducer, transmembrane, transmembrane helix, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCell membrane ; Multi-pass membrane protein  Q14832
Total number of polymer chains1
Total molecular weight55415.11
Authors
Primary citation
Wernimont, A.K.,Dong, A.,Seitova, A.,Crombet, L.,Khutoreskaya, G.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Weigelt, J.,Cossar, D.,Dobrovetsky, E.
Crystal Structure of Metabotropic glutamate receptor 3 precursor in presence of LY341495 antagonist
TO BE PUBLISHED,
Experimental method
X-RAY DIFFRACTION (2.26 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.238203.3%7.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report