3SLZ

The crystal structure of XMRV protease complexed with TL-3

Summary for 3SLZ

Entry DOI	10.2210/pdb3slz/pdb
Related	3NR6 3SM1 3SM2
Related PRD ID	PRD_000434
Descriptor	gag-pro-pol polyprotein, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate, FORMIC ACID, ... (5 entities in total)
Functional Keywords	beta sheet and dimer, protease, peptide inhibitor, tl-3 pepstatina, virus, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	DG-75 Murine leukemia virus
Total number of polymer chains	2
Total formula weight	29898.80
Authors	Li, M.,Gustchina, A.,Wlodawer, A. (deposition date: 2011-06-27, release date: 2011-10-12, Last modification date: 2024-02-28)
Primary citation	Li, M.,Gustchina, A.,Matuz, K.,Tozser, J.,Namwong, S.,Goldfarb, N.E.,Dunn, B.M.,Wlodawer, A. Structural and biochemical characterization of the inhibitor complexes of xenotropic murine leukemia virus-related virus protease. Febs J., 278:4413-4424, 2011 Cited by PubMed: 21951660 DOI: 10.1111/j.1742-4658.2011.08364.x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation