3SLZ

The crystal structure of XMRV protease complexed with TL-3

3SLZ の概要

• エントリーDOI: 10.2210/pdb3slz/pdb
• 関連するPDBエントリー: 3NR6 3SM1 3SM2
• 関連するBIRD辞書のPRD_ID: PRD_000434
• 分子名称: gag-pro-pol polyprotein, benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate, FORMIC ACID, ... (5 entities in total)
• 機能のキーワード: beta sheet and dimer, protease, peptide inhibitor, tl-3 pepstatina, virus, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: DG-75 Murine leukemia virus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 29898.80

構造登録者

Li, M.,Gustchina, A.,Wlodawer, A. (登録日: 2011-06-27, 公開日: 2011-10-12, 最終更新日: 2024-02-28)

• 主引用文献: Li, M.,Gustchina, A.,Matuz, K.,Tozser, J.,Namwong, S.,Goldfarb, N.E.,Dunn, B.M.,Wlodawer, A.; Structural and biochemical characterization of the inhibitor complexes of xenotropic murine leukemia virus-related virus protease.; Febs J., 278:4413-4424, 2011; PubMed: 21951660; DOI: 10.1111/j.1742-4658.2011.08364.x

実験手法

X-RAY DIFFRACTION (1.4 Å)