3SJ9

crystal structure of the C147A mutant 3C of CVA16 in complex with FAGLRQAVTQ peptide

Summary for 3SJ9

• Entry DOI: 10.2210/pdb3sj9/pdb
• Related: 1CQQ 1L1N 2ZTY 3SJ8 3SJI 3SJK 3SJO
• Descriptor: 3C protease, FAGLRQAVTQ peptide (3 entities in total)
• Functional Keywords: binding to its substrate-peptide, chymotrypsin-like fold, protease, hydrolase
• Biological source: Human coxsackievirus A16
• Total number of polymer chains: 2
• Total formula weight: 22149.36

Authors

Lu, G.,Qi, J.,Chen, Z.,Xu, X.,Gao, F.,Lin, D.,Qian, W.,Liu, H.,Jiang, H.,Yan, J.,Gao, G.F. (deposition date: 2011-06-21, release date: 2011-08-10, Last modification date: 2023-09-13)

• Primary citation: Lu, G.,Qi, J.,Chen, Z.,Xu, X.,Gao, F.,Lin, D.,Qian, W.,Liu, H.,Jiang, H.,Yan, J.,Gao, G.F.; Enterovirus 71 and Coxsackievirus A16 3C Proteases: Binding to Rupintrivir and Their Substrates and Anti-Hand, Foot, and Mouth Disease Virus Drug Design.; J.Virol., 85:10319-10331, 2011; PubMed: 21795339; DOI: 10.1128/JVI.00787-11

Experimental method

X-RAY DIFFRACTION (2.399 Å)