3SF8

Structural insights into thiol stabilization of DJ-1

3SF8 の概要

• エントリーDOI: 10.2210/pdb3sf8/pdb
• 分子名称: Protein DJ-1 (3 entities in total)
• 機能のキーワード: oxidative stress, redox regulation, cysteine oxidation, protecting dj-1 oxidation, reduced dj-1, class i glutamine amidotransferase family, cytoprotective activity against oxidative stress; cysteine sulfenic acid modification, hydrolase, oncoprotein, unknown function
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: Q99497 Q99497
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 40334.64

構造登録者

Premkumar, L.,Dobaczewska, M.K.,Riedl, S.J. (登録日: 2011-06-13, 公開日: 2011-10-05, 最終更新日: 2023-12-06)

• 主引用文献: Premkumar, L.,Dobaczewska, M.K.,Riedl, S.J.; Identification of an artificial peptide motif that binds and stabilizes reduced human DJ-1.; J.Struct.Biol., 176:414-418, 2011; PubMed: 21893204; DOI: 10.1016/j.jsb.2011.08.011

実験手法

X-RAY DIFFRACTION (1.56 Å)