3SEM

SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR

3SEM の概要

• エントリーDOI: 10.2210/pdb3sem/pdb
• 分子名称: SEX MUSCLE ABNORMAL PROTEIN 5, SH3 PEPTOID INHIBITOR (3 entities in total)
• 機能のキーワード: sh3 domain, inhibitors, peptoids, protein-protein recognition, proline-rich motifs, signal transduction, signaling protein-inhibitor complex, signaling protein/inhibitor
• 由来する生物種: Caenorhabditis elegans
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 16178.04

構造登録者

Nguyen, J.T.,Turck, C.W.,Cohen, F.E.,Zuckermann, R.N.,Lim, W.A. (登録日: 1998-11-02, 公開日: 1999-01-06, 最終更新日: 2023-11-15)

• 主引用文献: Nguyen, J.T.,Turck, C.W.,Cohen, F.E.,Zuckermann, R.N.,Lim, W.A.; Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors.; Science, 282:2088-2092, 1998; PubMed: 9851931; DOI: 10.1126/science.282.5396.2088

実験手法

X-RAY DIFFRACTION (2.2 Å)