3S8M

The Crystal Structure of FabV

3S8M の概要

• エントリーDOI: 10.2210/pdb3s8m/pdb
• 分子名称: Enoyl-ACP Reductase (2 entities in total)
• 機能のキーワード: rossmann fold, oxidoreductase, nadh binding, fatty acid synthesis, enoyl-acp
• 由来する生物種: Xanthomonas oryzae pv. oryzae
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 46247.07

構造登録者

Li, H.,Zhang, X.L.,Bi, L.J.,He, J.,Jiang, T. (登録日: 2011-05-29, 公開日: 2011-11-16, 最終更新日: 2024-10-16)

主引用文献

Li, H.,Zhang, X.,Bi, L.,He, J.,Jiang, T.
Determination of the Crystal Structure and Active Residues of FabV, the Enoyl-ACP Reductase from Xanthomonas oryzae.
Plos One, 6:e26743-e26743, 2011

PubMed Abstract: Enoyl-ACP reductase (ENR) catalyses the last reduction reaction in the fatty acid elongation cycle in bacteria and is a good antimicrobial target candidate. FabV is the most recently discovered class of ENR, but we lack information about the atomic structure and the key residues involved in reductase activity except for the known conserved tyrosine and lysine residues in the Y-X(8)-K active site motif.

PubMed: 22039545
DOI: 10.1371/journal.pone.0026743

実験手法

X-RAY DIFFRACTION (1.6 Å)