3ROO

Murine class I major histocompatibility complex H-2Kb in complex with immunodominant LCMV-derived gp34-41 peptide

3ROO の概要

• エントリーDOI: 10.2210/pdb3roo/pdb
• 関連するPDBエントリー: 1S7Q 3ROL
• 分子名称: H-2 class I histocompatibility antigen, K-B alpha chain, Beta-2-microglobulin, Pre-glycoprotein polyprotein GP complex, ... (7 entities in total)
• 機能のキーワード: t-cell receptor, mhc, gp34, ny-gp34, epitope, post-translational modification, lcmv, mhc class i, immune escape, immune system, t cell recognition, autoimmunity, t cell receptor, cell surface
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Secreted: P01901
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 89406.18

構造登録者

Madhurantakam, C.,Duru, A.D.,Leong, C.,Sandalova, T.,Webb, J.R.,Achour, A. (登録日: 2011-04-26, 公開日: 2012-04-04, 最終更新日: 2024-11-20)

• 主引用文献: Madhurantakam, C.,Duru, A.D.,Leong, C.,Sandalova, T.,Webb, J.R.,Achour, A.; Nitro-tyrosination of the immunodominant LCMV epitope gp34-41 alters both its capacity to stabilize H-2Kb and the molecular surface of the MHC complex, affecting TCR recognition; PLoS ONE, 2012

実験手法

X-RAY DIFFRACTION (2 Å)