3RIG
Sirt5 is an NAD-dependent protein lysine demalonylase and desuccinylase
Summary for 3RIG
Entry DOI | 10.2210/pdb3rig/pdb |
Related | 3RIY |
Descriptor | NAD-dependent deacetylase sirtuin-5, peptide of histone 3 thioacetyl-lysine 9, ZINC ION, ... (5 entities in total) |
Functional Keywords | protein lysine demalonylase/desuccinylase, zn-binding domain, rossmann fold, mitochondria, hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Mitochondrion matrix. Isoform 1: Cytoplasm . Isoform 2: Mitochondrion : Q9NXA8 |
Total number of polymer chains | 4 |
Total formula weight | 62482.02 |
Authors | Zhou, Y. (deposition date: 2011-04-13, release date: 2011-11-23, Last modification date: 2023-11-01) |
Primary citation | Du, J.,Zhou, Y.,Su, X.,Yu, J.J.,Khan, S.,Jiang, H.,Kim, J.,Woo, J.,Kim, J.H.,Choi, B.H.,He, B.,Chen, W.,Zhang, S.,Cerione, R.A.,Auwerx, J.,Hao, Q.,Lin, H. Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase Science, 334:806-809, 2011 Cited by PubMed: 22076378DOI: 10.1126/science.1207861 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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