3RI5
C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab, ivermectin and picrotoxin
Summary for 3RI5
Entry DOI | 10.2210/pdb3ri5/pdb |
Related | 3RHW |
Descriptor | Avermectin-sensitive glutamate-gated chloride channel GluCl alpha, (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-2a-hydroxy-8b-methyl-9-(prop-1-en-2-yl)hexahydro-3,6-methano-1,5,7-trioxacyclopenta[ij]c yclopropa[a]azulene-4,8(3H)-dione, Mouse monoclonal Fab fragment, heavy chain, ... (10 entities in total) |
Functional Keywords | membrane protein, transport protein, cys-loop receptor, ligand-gated ion channel, neurotransmitter receptor, ivermectin, picrotoxin, glycosylation, transport protein-immune system complex, transport protein/immune system |
Biological source | Caenorhabditis elegans (nematode) More |
Total number of polymer chains | 15 |
Total formula weight | 438280.31 |
Authors | Hibbs, R.E.,Gouaux, E. (deposition date: 2011-04-12, release date: 2011-05-25, Last modification date: 2023-09-13) |
Primary citation | Hibbs, R.E.,Gouaux, E. Principles of activation and permeation in an anion-selective Cys-loop receptor. Nature, 474:54-60, 2011 Cited by PubMed: 21572436DOI: 10.1038/nature10139 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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